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Bruce Fielder (born 1 November 1992), known professionally as Sigala, is an English DJ, record producer and remixer from Norwich, Norfolk.

Sigma are a British drum and bass DJ and record production duo consisting of Cameron James "Cam" Edwards and Joseph Aluin "Joe" Lenzie.

Sigrid Solbakk Raabe (born 5 September 1996) is a Norwegian singer and songwriter.

Sigur Rós is an Icelandic post-rock band from Reykjavík, active since 1994.

Richard Lamar Hawk (born January 22, 1998), better known as Silentó or Prince Silentó, is an American rapper.

Silverchair were an Australian rock band, which formed in 1992 as Innocent Criminals in Newcastle, New South Wales with Ben Gillies on drums, Daniel Johns on vocals and guitars, and Chris Joannou on bass guitar.

Silverstein is a Canadian rock band from Burlington, Ontario, formed in 2000.

Silversun Pickups is an American alternative rock band from Los Angeles that was formed in 2000.

Simian Mobile Disco are an English electronic music duo and production team, formed in 2003 by James Ford and Jas Shaw of the band Simian.

Simon & Garfunkel were an American folk-rock duo consisting of singer-songwriter Paul Simon and singer Art Garfunkel.

Simple Creatures is an American pop rock duo that was formed by vocalist, bassist, and keyboardist Mark Hoppus of Blink-182 and vocalist, guitarist, and keyboardist Alex Gaskarth of All Time Low.

Simple Minds are a Scottish rock band formed in Glasgow in 1977.