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Simple Plan is a Canadian rock band from Montreal, Quebec formed in 1999.

Simply Red are a British soul and pop band which formed in Manchester in 1985.

Sinéad Marie Bernadette O'Connor (born 8 December 1966) is an Irish singer-songwriter who rose to fame in the late 1980s with her debut album The Lion and the Cobra.

Siouxsie and the Banshees were a British rock band, formed in London in 1976 by vocalist Siouxsie Sioux and bass guitarist Steven Severin.

Anthony L. Ray (born August 12, 1963), better known by his stage name Sir Mix-a-Lot, is an American rapper, songwriter, and recording producer.

Mark Althavan Andrews (born November 9, 1978), better known by his stage name Sisqó, is an American R&B singer, songwriter, record producer, dancer and actor.

Sister Hazel is an American alternative rock band from Gainesville, Florida, whose style blends elements of jangle pop, folk rock, classic rock and southern rock.

Sixpence None the Richer (also known as Sixpence) is an American Christian alternative rock band that formed in New Braunfels, Texas, eventually settling in Nashville, Tennessee.

Sixx:A.M. is a hard rock band from Los Angeles, California, formed in 2007 by Nikki Sixx, DJ Ashba, and James Michael, and was a side project of Sixx, who was also at the time bass guitarist for Mötley Crüe.

Antoine Roundtree (born March 27, 1975), better known by his stage name Skee-Lo, is an American rapper.

Joseph Junior Adenuga (born 19 September 1982), known professionally as Skepta, is a British MC, rapper, songwriter and record producer from Tottenham, North London.

Stokeley Clevon Goulbourne (born April 18, 1996), known professionally as Ski Mask the Slump God (formerly stylized as $ki Mask "The Slump God"), is an American rapper and songwriter.