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Soft Cell were an English synthpop duo who came to prominence in the early 1980s.

Soil – often typeset as SOiL – is an American rock band that was formed in Chicago, Illinois in 1997.

Solange Piaget Knowles (born June 24, 1986), also known mononymously as Solange, is an American singer, songwriter, record producer, performance artist, and actress.

Something Corporate (also known as SoCo) was an American rock band from Orange County, California, formed in 1998.

Sonata Arctica is a Finnish power metal band from the town of Kemi, Finland.

Sonic Youth was an American rock band based in New York City, formed in 1981.

Sophia Grace Brownlee (born 18 April 2003) and her cousin Rosie McClelland (born 7 September 2006), both from Essex, England, make up the duo Sophia Grace & Rosie. They quickly gained popularity, by making regular appearances on The Ellen DeGeneres Show, after posting a cover version of the Nicki Minaj song "Super Bass" that became popular on YouTube.

Sophie Ballantine Hawkins (born November 1, 1964) is an American singer-songwriter, musician and painter, born in New York City.

Sophie Michelle Ellis-Bextor (born 10 April 1979) is an English singer, songwriter and model.

Soul Asylum is an American alternative rock band formed in 1981 in Minneapolis, Minnesota.

Soulfly is an American heavy metal band formed in Phoenix, Arizona in 1997.

DeAndre Cortez Way, better known as Soulja Boy Tell 'Em or simply Soulja Boy, is an American rapper, record producer, actor and entrepreneur.