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Sam Lowry Hunt (born December 8, 1984) is an American singer and songwriter.

Samuel Frederick Smith (born 19 May 1992) is an English singer and songwriter.

Samuel Falson (born 8 November 1982), better known by his stage name Sam Sparro, is an Australian singer, songwriter and record producer.

Sam and the Womp is a British pop group consisting of trumpeter Sam Ritchie and Dutch-born vocalist Bloem de Ligny, also known as Lady Oo.

Sami Yusuf (born July 1980) is a British singer, songwriter, multi-instrumentalist, composer, record producer, and humanitarian, born in Tehran, Iran.

Samuel Adams Wisner (born August 14, 1987) is an American rapper, singer and songwriter.

Samuel Roy Hagar (born October 13, 1947), also known as The Red Rocker, is an American rock vocalist, songwriter, musician, and entrepreneur.

Sampha Lahai Sisay (born 16 November 1988) is an English singer, songwriter, musician and record producer from Morden, South London.

San Cisco is an Australian indie pop band that formed in 2009 under the original name of King George, in Fremantle, Western Australia.

San Fermin is an American indie rock collective, led by Brooklyn-based composer and songwriter Ellis Ludwig-Leone.

Sananda Francesco Maitreya (born Terence Trent Howard, March 15, 1962), better known by his former stage name Terence Trent D'Arby, is an American singer and songwriter.

Sanctus Real is an American Christian rock band formed in Toledo, Ohio, in 1996.