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Sharon Katharine Van Etten (born February 26, 1981) is an American singer-songwriter and actress.

Shawn Colvin (born Shawna Lee Colvin, January 10, 1956) is an American singer-songwriter and musician.

Shawn Peter Raul Mendes (born August 8, 1998) is a Canadian singer and songwriter.

Shayne Thomas Ward (born 16 October 1984) is an English singer and actor.

She & Him is an American musical duo consisting of Zooey Deschanel (vocals, piano, ukulele) and M. Ward (guitar, production).

She Wants Revenge is an American rock band, based in San Fernando Valley, California and formed in 2004.

Khadimou Rassoul Cheikh Fall (born September 10, 1998), better known as Sheck Wes, is an American rapper, singer, songwriter, and model.

Sheppard is an Australian indie pop band from Brisbane, formed in 2009.

Sheridan Smith, (born 25 June 1981) is an English actress and singer.

Sheryl Suzanne Crow (born February 11, 1962) is an American musician, singer, songwriter, and actress.

Lewis Shay Jankel (born 27 May 1993), known by his stage name Shift K3Y, is a British DJ, record producer, singer and songwriter, from London.

Shinedown is an American rock band from Jacksonville, Florida, formed by singer Brent Smith in 2001 after the dissolution of Dreve, his previous band.